VCA Main Street Animal Hospital

4.4 (176)
2773 Main St, San Diego, CA 92113, USA

Hours:

Monday: 8:00 AM – 5:30 PM

Tuesday: 8:00 AM – 5:30 PM

Wednesday: 8:00 AM – 5:30 PM

Thursday: 8:00 AM – 5:30 PM

Friday: 8:00 AM – 5:30 PM

Saturday: Closed

Sunday: Closed

How to Save Money at VCA Main Street Animal Hospital

Schedule Regular Vet Visits

One of the best ways to save on vet bills is to prevent expensive health issues before they develop. By scheduling regular wellness checkups, your vet can detect health issues early, helping you to avoid costly treatments and surgeries down the road.

Price Shop for Pet Prescriptions

Oftentimes our fur babies are prescribed human drugs off-label. Your vet is apt to charge more for these medications than you would pay at your local pharmacy. In fact, big-box or chain pharmacies can offer steep discounts. So it’s best to price shop.

Pet Insurance

Most pet insurance providers will pay between 80% and 90% of the vet bill. You can even get coverage for routine care and things like vaccinations and dental cleanings. If you do the math, you’ll most likely find that pet insurance makes financial sense in the long run as well as gives you peace of mind.

How Do You Choose the Right Pet Insurance Provider?

Pet Insurance Review makes it incredibly easy for pet parents to select an insurance provider they feel good about. You can use our handy comparison tool to get the gist of what a company offers. We’ve also collected over 150,000 reviews of insurance companies from real pet parents like you to rank the top providers in the market. Here is the current ranking of each:

Top Pet Insurance Providers of 2026
Rating Provider Total Review
4.5 AKC 1,797
4.5 ASPCA 12,110
4.9 Embrace 19,785
4.9 Fetch 5,400
4.1 Figo 2,832
4.5 Hartville 179
4.9 Healthy Paws 11,071
4.8 Lemonade 822
4.6 ManyPets 2,413
4.7 MetLife 8,716
4.8 Nationwide 24,889
3.9 Pet Assure 15
4.3 PetPartners 121
4.9 Pets Best 8,940
4.8 Pumpkin 3,153
4.6 Spot 10,949
4.9 Trupanion 55,032
4.8 Prudent Pet 2,695
4.5 Adoro 6

Or, you can simply get a fast quote from multiple providers and go from there.

Thinking of insuring your pet?

Get Quotes & Compare

Getting to Know Your New Vet: Essential Questions to Ask

Choosing a new veterinarian is an important decision for any pet owner. You want to find someone who is competent, compassionate, and a good fit for you and your fur baby. To help you get the most out of your first appointment, here's a list of essential questions to ask your new vet:

Tell me about your experience with [pet type].

Different vets have different areas of specialization. Some are experts with cats, some dogs, some pocket pets, and some horses. Knowing that your vet has vast experience treating your specific type of pet can bring you peace of mind.

How do you handle emergencies?

You must know what to do in case of a pet medical emergency. Inquire what after-hours policy the clinic has, whether they have on-site emergency care available, and if they have a relationship with any nearby emergency animal hospitals.

How do you communicate with pet owners?

Good communication is key to building a trusting relationship with your vet. Ask how they prefer to communicate (phone calls, emails, online portal) and how often you can expect to hear from them.

Are there any breed-specific health concerns I should be aware of?

Some breeds are predisposed to certain health conditions. Knowing what to watch out for can help you catch problems early and get your pet the treatment they need.

Do you have any questions for me about my pet?

This is a great question to ask because the answer will show that the vet is interested in getting to know your pet as an individual and is willing to listen to your concerns.

Bonus question: Can I take a tour of your facility?

Getting a feel for the clinic's environment can help you and your pet feel more comfortable during your visits. Remember, you’re not just looking for a veterinarian, you’re looking for a partnership. Do not be afraid to ask these questions and any others you can think of. Any vet worth their salt will be happy to answer them. Because the more informed you are, the better equipped you'll be to make decisions about your pet's care! And that should be every vet’s top priority.

Reviews from Google

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Alexis Dominguez

I can’t say enough wonderful things about VCA Main Street Animal Hospital! From the moment we walked in, the staff was warm, welcoming, and genuinely caring. The front desk made check-in easy and stress-free, and the technicians were so gentle and kind with my pet. The doctors took the time to really listen, explain everything clearly, and answer all of my questions. You can truly tell they love what they do and have a passion for animals. The level of care here is outstanding—they go above and beyond to make sure both pets and owners feel comfortable and confident. I left feeling so reassured knowing my pet was in the best hands possible. Highly recommend this hospital to anyone looking for compassionate, professional, and top-quality veterinary care!

posted: 10/03/2025

John Wherry

The family cat Zeus add a red spot on his backside that seems to be inflamed we found it Friday but spent the weekend trying to get him in to see a vet. Finally I got a hold of VCA main Street hospital and got them a appointment on the same day. It was a quick consultation and medicine was given to Zeus to make him feel better. We are so happy we got him seen today. Much love to the VCA system and the main street address in particular.

posted: 11/03/2025

Meagan Balumbu

I've been coming here the last year and was recommended by my work to come here. As our work cats are treated here. The communication last year became terrible. No updates after appointments before we left, no communication. I discussed this with her doctor. Communication became better for a brief while, sadly our doctor left. I got a call back from the doctor over 30 hours of waiting last week!! A brief conversation not much plan other than keep my cat on probiotics for the month. This was after being in urgent care and having my cat hydrated and given medication. The vet is closed on Saturday now which seems to have slowed service down and made communication even worse. Again we are sitting in the specialty urgent care to see about a possible food allergy as my cat puked this morning. Since I cant get into the vet for help any sooner than the 20th now, and dont get much resolve via phone either. This is disappointing as we are paying for packages and not receiving good care. The emergency line is just as bad very flat rude, and uncaring. The only place I seem to be able to get help now is the specialty urgent care. We wait for hours pay extra and its only way I can see to get help. Or receive any call backs/action plans is from the specialty care. I dont know what's going on it's disappointing, and poor service.

posted: 10/12/2025

Alex Jimenez

My first time here and it was great, brought my cat Logan and everyone was so nice to him, definitely felt like I(Logan) was gonna be taken care of. Staff was excellent and Dr Bardini was very reassuring and did not try pressuring me into any treatment, simply explained the options and was open to any of my questions. I left feeling a lot less worried than I was when I got there. I called around lunch time looking for a same day appointment and while all other vets left me on hold, this was not the case here, they listened to me and helped me. I will be switching my puppy’s vet to this location for her next check up.

posted: 08/08/2024

Susan Strauel

I've been taking my pets there for a while they are gracious friendly and they love their animals very clean and very nice place to take your pet

posted: 01/31/2026