Appa was a Great Pyrenees mix that we adopted from a rescue. In the one year we had him, he tore his ACL and was diagnosed with bone cancer.
In total Appa’s medical care cost about $15k while he was in our care and Trupanion covered 90% of that amount without complaint or hassle. The only thing they don't cover is examinations, which is kind of a pain, but honestly the exam was usually $60-100 and the actual medical service was several thousand so not a huge deal.
I would recommend Trupanion to any pet owner.